IR spectra were collected with Nicolet iN10 MX spectrometer. Bruker ESQ 3000 high resolution mass determinations: Bruker APEX III FTMS (7 T magnet)). EI+-MS were recorded with Agilent Technologies 5973N, EI+-HRMS were recorded with Waters Micromass GCT Premier, and the electron energy was 70eV. ESI+-HRMS spectra were recorded with Bruker APEXIII 7.0 TESLA FTMS. "There is simply nothing like ultra-high field FTMS anywhere else."Ī modified Bruker Daltonics APEX FTMS system, equipped with a 9.4 Tesla superconducting magnet, has already been used at the DOE Pacific Northwest National Laboratory to characterize a bacterial proteome in 3 hours using accurate mass measurements and automated MS/MS. MALDI-HRMS were recorded with IonSpec 4.7T.
"Our development of this ultra-high resolving power FTMS approach will help unravel the entire human proteome," Muddiman said in a statement. In fact, Bruker today began installing the 12 Tesla superconducting magnet, a process that is scheduled to wrap up next month.Īccording to Bruker, the 12 Tesla APEX FTMS system will be Mayo's primary technology for studying the human proteome. Keck FT-ICR mass spec lab, is expected to "further develop the applications of ultra-high field FTMS," the partners said.Īs part of the deal, Bruker has given the Mayo what is believed to be the world's first commercial 12 Tesla FTMS system, customized for proteome-wide measurements. The collaboration between Bruker and David Muddiman, director of Mayo's W.M. Specifications: Superconducting 7T magnet. 27 - Bruker Daltonics and the Mayo Clinic have partnered to develop new methods for protein analysis using Fourier transform mass spectrometry, Bruker said today. Our FTMS system is a 7T solariX XR FT-ICR-MS coupled to a MALDI source equipped with a Smartbeam II laser (Bruker Daltonik, Bremen). Advances in Clinical Genomics Profiling.
0 kommentar(er)
